KMID : 0359320110510010007
|
|
Korean Journal of Veterinary Research 2011 Volume.51 No. 1 p.7 ~ p.14
|
|
Quantification and genotyping of PCV2 DNA in the tissues of PCV2-infected conventional pigs with different clinical signs
|
|
Kim Hye-Kwon
Luo Yuzi Moon Hyoung-Joon Park Seong-Jun Rho Se-Mi Han Jae-Yeon Van Giap Nguyen Park Bong-Kyun
|
|
Abstract
|
|
|
This study was focused on the genotyping and quantification of Porcine circovirus type 2 (PCV2) in thirty PCV2-positive pigs with different clinical symptoms (PCV2-infected without wasting, PCV2-infected with wasting, PCV2-infected with wasting and lymphoid depletion). The quantity of PCV2 DNA in diverse tissues was significantly differed among these groups. (One-way ANOVA test, p < 0.001) Interestingly, PCV2-DNA load in tissues of PCV2-infected pigs without wasting and PCV2-infected pigs with wasting and lymphoid depletion were not significantly differed (p = 0.38), while they were all significantly higher when compared with PCV2-infected pigs with wasting-only. PCV2 DNA quantity in tissues was significantly higher in PCV2a and 2b co-infected pigs compared to the PCV2b only-infected pigs (Wilcoxon test, p = 0.039). The PCV2a and 2b co-infected pigs had increased wasting and lymphoid depletion rate but it was not statistically significant. Therefore, this cross-sectional study suggested that PCV2 DNA load in tissues was diverse by clinical and histological findings. Furthermore, co-infection of PCV2a and 2b affected to the PCV2 DNA load in tissues with increased rate of wasting and lymphoid depletion.
|
|
KEYWORD
|
|
clinical sign, genotype, PCV2a, PCV2b, quantification
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|